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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

Key projected targets for development this year:
3.50 First Dates

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

目前,中国15座城市允许对某些国家的公民实行72小时免签证入境。上海、江苏和浙江则为来自某些国家的国际过境旅客提供144小时免签证停留。
Iron Man was Downey’s only movie of 2013, while Johnson had one huge film, Fast & Furious 6; one big film, G.I. Joe: Retaliation; and two smaller films. Together they added up to $1.3 billion at the global box office.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
From the themed collection: 港澳居民适龄随迁子女可申请入读
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 开年大盘点:木材利润哪个高?
Open Access Perspective

Soft matter science and the COVID-19 pandemic

QK%.jd&KnAkQ

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: “两会”促进绿色建材大力发展
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

Wardrobe malfunctions was another common theme. Some hapless interviewees “showed up in sweatpants,” one “was wearing mismatched shoes,” and another “didn’t realize his zipper was down.”

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

"You're part of the past, but now you're the future," Lana Del Rey sings on Lust for Life's opening track, "Love".
vi. & vt
Let’s now travel to Greece. There, Andreas Georgiou, the head of its statistical agency between 2010 and 2015, faces prosecutions for his part in uncovering fake Greek public finance data for 2009 and setting the record straight. This week 40 groups, led by the American Statistical Association, and 651 individuals signed a statement in support of Mr Georgiou.
4. Booing isn't just for pantomimes

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

Banks, asset managers and insurance companies have flocked from mainland China to acquire prime Hong Kong office buildings, prompting the territory’s government to announce it will release more land for commercial redevelopment in the oversubscribed heart of the city.
谎言9:对,我在高中足球队里就是个捣蛋鬼!说谎原因:我想让自己在别人的眼里更加闪亮。
莱斯特大学研究人员表示,这副骸骨的DNA同理查三世一名姐妹的后代吻合,而且骸骨的脊柱弯曲,有战争留下的创伤,这都与历史记载吻合。
在即将结束的2014年,标普500指数再次实现亮眼增长,而那些本欲跑赢该指数的基金经理们,表现则没那么出色。Lipper公司称,截止11月底,85%的活跃股票型共同基金经理业绩低于标普500指数。而在正常的年份里,跑赢该指数的基金经理比例是今年的两倍,也就是说,通常只有约三分之二的基金表现不如标普500指数。Lipper公司称,这是30年来活跃基金经理相对大盘表现最差的一年。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

“这不是可持续的增长,因为它们并未被租出去,当地市场的喊价者们并不会购买。”

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

In the 1990s, Roth applied it to the market for allocating US student doctors to hospitals. He developed a new algorithm that was adopted by the National Resident Matching Program, which helps match resident doctors with the right hospitals.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

9.Yeah, I was a badass on my high school football team! – Because I want to be seen by others in an even stronger light than I see myself。
adj. 聪明的,时髦的,漂亮的,敏捷的,轻快的,整洁的

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

开发商:Remedy Entertainment、Microsoft Studios
节目20 小品《今天的幸福2》,沈腾 马丽 杜晓宇 王琦

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

3.5 促进农业稳定发展和农民持续增收
A disturbing and often bleak analysis of the automated future of work has been named 2015’s business book of the year.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

德系三巨头:由于奔驰的几款低价产品不可避免地会损害它“要么最好,要么什么都不是”(the best or nothing)的商誉,该公司也开始陷入低迷。而即将推出的新7系轿车则会进一步巩固宝马在美国富人圈中的地位。另外,起价30,795美元的奥迪A3,很可能会使奥迪的销量较2014年增长15%,新款Q7也将进一步提高奥迪的利润。
But with a Republican-controlled State Senate, opponents of rent stabilization doubt that 2015 will be a watershed year for the tenants’ movement. Sherwin Belkin, a lawyer who represents landlords, said: “Landlords view this as an opportunity to make some much-needed changes to rent regulation.”
让自己坐的舒适。在弄了这么多之后,最重要的一点是要让自己感觉到很舒适。
小女孩名叫Neshama Spielman,来自耶路撒冷。她是4年前在“圣殿山筛选项目”中发现这个护符的。该项目旨在检查从神圣犹太教遗址移来,未经考古检测过的泥土。当年,Spielman只有8岁。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

节目9 相声《这事儿不赖我》,曹云金 刘云天

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
From the themed collection: 防止用于减税资金变成“唐僧肉”
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

这篇文章发表后,美国参议院很快投票通过了《反就业歧视法》(Employment Non-Discrimination Act)。这样,在工作中歧视LGBT群体也有可能成为违法行为。这项法案即将提交众议院审议。
There are 27 companies that are dropped from the list this year, including AT&T, IBM, Siemens and Xerox.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

I can't stop thinking that these children are my age, that it makes a tremendous difference where you are born, that I could be one of those children living in the Favellas of Rio; I could be a child starving in Somalia; a victim of war in the Middle East or a beggar in India. 我永远不能忘记这些和我同龄的孩子,当你出生的时候,他和我们真的很不相同,我也许生活在贫民窟,也可能是终日饿着肚子的小孩,也可能是中东战争的牺牲品,或者印度的小乞丐。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

The magazine put his net worth at $3.5 billion, down $1 billion from the rankings it issued a year ago.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
From the themed collection: 2020年我国智慧社区将达五成
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

7. “The Kindergarten Teacher” In his tough, weird knockout, the Israeli director Nadav Lapid spins the story of a teacher’s obsession with a child poet to create a savage portrait of fanaticism and its costs.
007系列电影主题曲第一名:雪莉·巴赛--《金手指》
ordering
然后,他用那把小提琴砸穿了那幅画。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

美国的药品支出费用约占总量三分之一,据艾美仕研究所专家估计,2014年这个数值将上升11.7个百分点。据报道,美国的药品支出费用价格特别高,但制药商解释说这是由于研制新药的成本猛增。
headway
作为每年都会有超过100万人参加的国家级考试,研究生入学考试对于学生的学习生涯是非常重要的,而作弊事件也一而再再而三被曝光。
2. “Inside Out” (Pete Docter)
周二在华盛顿DC的乔治市附近,人们沿着被淹的波托马克河在雨中漫步。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

n. 块,大量,众多
The top obsession of 2010 was the much-anticipated iPhone, followed by actress Lindsay Lohan, the iPad, and the television shows "Glee" and "Jersey Shore".

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

“在ETF壮大的地区(美国和欧洲),有一个庞大的理财顾问生态系统,”他表示,“你需要一个更加依靠顾问的模式。但在你看到人们为建议付费(而不是支付佣金)之前,很难设想它何时起飞。”

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

His strategic shift away from corporate strategy was in spite of the fact that his own school had deterred him from making a career in education, even though he had worked as a private tutor.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

France, one of the most visited countries in the world, ranks No. 9 overall. It is No. 2 in Cultural Influence and No. 6 in Power.
在这个越来越为人类所主宰的星球上,我们仍然可以从其他物种身上学习到很多东西。格陵兰鲨鱼可存活400年,是世界上最长寿的脊椎动物,这一发现让人类重新审视自己忙碌的人生。
3. Not starting your own business
n. 警戒,警惕

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

The CPI rose by 2 percent.
Mr. Russell's 1970s Abscam fictionalization 'American Hustle' had the better night overall, winning acting awards for Amy Adams and Jennifer Lawrence. Best picture was the only award for '12 Years a Slave,' which came in with seven nominations, tied for the most with 'American Hustle.'
时间:2012-02-02 编辑:Jasmine
On the sales front, General Motors and Ford F -0.13% lost market share to Chrysler, which leveraged its Jeep brand to previously unimagined heights – and then, metaphorically left its heritage behind when it established legal domicile in the Netherlands and changed its name to FCA US LLC.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

其次,尽管人们还守着老的观念,现实却已经发生了变化:供应链管理——也就是确保货物以尽可能低的价格和尽可能高的效率到达目的地——已经成为一项高科技、高风险的行业了。它要求从业者“硬件能力”和“软件能力”缺一不可,而能达到这种要求的人才实在很少。
There are legitimate reasons to doubt that Nerlens Noel can blossom into a dependable starting center, including his injury history, off-court red flags, and extremely limited offensive game.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

最佳迷你剧/电影:《美国罪案故事:公诉辛普森》(“The People v. O. J. Simpson: American Crime Story”, FX)
The country has rolled out measures to promote new-energy vehicles, including tax exemptions, subsidies for car purchases and a requirement for government departments to buy more new-energy cars.
伊格尔说:“他非常、非常善于不让这些压力以任何方式破坏苹果正在努力实现的目标。库克的脑海里无疑有要操心的问题,但他确保专门从事苹果最擅长工作的人才不必操心这些问题。”
Originally intended for the opening credits of Tomorrow Never Dies, and then for some reason relegated to the closing credits, K.D. Lang's "Surrender" is silken and cool. The horn sections are sassy and powerful. It's one of the best James Bond theme songs, and it's not even officially a James Bond theme song. And it's a heck of a lot better than the official theme the movie finally got.
"He was not on the intelligence services' radar," added the prime minister.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

['?nim'pl?im?nt]
OUTDOOR SPACE: The property is just shy of an acre and a half.
为了尝试遏制煤炭消耗量的增长,中国正在可再生能源和核能领域投入巨资,但尽管付出了这些努力,中国迄今为止依然是最大的温室气体排放国。中国每年因化石燃料燃烧和水泥生产排放100亿吨二氧化碳,几乎是美国的两倍,但美国的人均排放量依然远远高于中国。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

今年11月,我国网约车司机将须通过考试获得从业资格证。
[.?pti'mistik]

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

Kate Hudson spoke to British Elle magazine exclusively for this interview。   凯特·哈德森接受了英国ELLE杂志对她的独家专访。Does actress Kate Hudson know wha
去年,酷热天气覆盖了阿拉斯加州和大部分美国西部地区。地面温度在所有有人居住的大陆上都创下了记录。科学家说,海洋表面在除南极洲附近海域以外的几乎所有水域中都异常温暖,为造成巨大破坏的太平洋风暴提供了能量。
I know a lot more about you when you walk in the door than you realize. I'll search for you on the web and often use my own personal network to do a pre-interview reference check.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
From the themed collection: 净水器行业大家居之路或可取
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

单词surrogate 联想记忆:
出手阔绰的美国公司正迫使英国同行提高从新入行者到顶级风云人物的薪资——尽管这并未阻止富尔德(Freshfields)的私募股权明星戴维希金斯(David Higgins)在圣诞节前夕跳槽到凯易律师事务所(Kirkland & Ellis)。精品专业律所通过提供更快、更专注的服务来吸引客户。
中国富人正在寻找属于自己的岛

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 调控精准发力推动经济稳中有进
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

李说,记者职业排名靠后已经有一段时间了(去年在200个职业中排名第196位)。他说,这次被挤到最后一位很可能是因为有些情况更糟了,如职业前景变差、平均薪资继续下滑、工作时间持续增加等,而且这些因素也让记者的压力更大。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

在毕业3年后的学员当中,男女毕业生薪资分别为9万美元和7.3万美元,相差近22%。刚完成学业时的男女毕业生薪资差距为17%,因此男女薪资差距随着时间推移而扩大(见图表)。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

周四,央视公布了2016猴年春晚的吉祥物后,就迅速成为互联网上的热议话题。不幸的是,不少网友称被其“丑哭”。
愿新年的烛光带给你祥和与喜悦,祝你新年充满爱。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

根据周一上海电视台的报道,2015年,上海市外来常住人口出现15年来的首次负增长。
库克已在先前以白人男性为主的苹果管理团队里增加了三位女性,还改变了苹果的董事会章程,承诺任命董事时会从少数群体中挑选候选对象。
If you've got children, I understand that this isn't always possible. Children should always come first. But if you don't show up for your classes, you're not getting that education we discussed in No. 1.
The Queen would have been down the stairs like a shot as soon as the aircraft came to a final halt.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

“I think the best way to engage young people in the process is to win,” he says.
在政府鼓励扩大对消费者和小企业融资的背景下,中国网上银行及P2P贷款行业迅速发展。目前中国P2P贷款领域有超过2000家公司。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

5. It's a dog's life for the British
Last week, Lu was appointed director of the office for Beijing's Leading Group of Promoting Beijing-Tianjin-Hebei Integration Development, a move to accelerate Beijing's moves to coordinate with Tianjin and Hebei province.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
From the themed collection: 新时代房企发展面临四维转型
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

该版猴票为我国发行的首套生肖邮票,因此颇受追捧。据悉,一枚邮票的价格已经从当时的发行价8分涨至1.2万元,整版价格更是达到150万元。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

"The online Internet anti-corruption bid mostly relies on text, photos and videos and it is easy to be superficial if corrupt officials are only exposed this way."
一份调查报告称,2014届中国大学毕业生的就业满意度为61%。
"People can be unhappy for many reasons -- from poverty to unemployment to family breakdown to physical illness," the report said. "But in any particular society, chronic mental illness is a highly influential cause of misery. If we want a happier world, we need a completely new deal on mental health."
This includes ‘qwerty,’ in fourth place, ‘admin,’ in 11th, and ‘login’, in 14th.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

弗拉德-迪瓦茨令人尴尬的新闻发布会,Vivek Ranadive对巴迪-希尔德的兴趣被透露,以及未能换回选秀权的多余球员。
产险公司利润同比下降43.49%,至336.57亿元人民币。寿险公司利润下降65.60%,至541.84亿元人民币,再保险公司利润下降58.79%,至30.68亿元人民币。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

凸起那部分有个“涡卷饰品”——(古埃及碑上)在王和神的名字周围的椭圆形装饰。考古学家在上面发现有眼镜蛇一只眼的符号。
From 'heelgate' to the Palm Dog to the 'Dad bod' – it's been a dizzying 12 days. Here are nine lessons from the film festival as it draws to a close.
Best Companies rank: 32

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
From the themed collection: 房企又抢地 二线城市仍是主战场
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

Morocco is a gateway to Africa. Major tourism cities in the North African kingdom include the capital of Rabat, Casablanca – the country's largest city - Marrakesh and Agadir.
['gri:nhaus]
n. 补给,供给,供应,贮备

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

我经常生气
单词trademark 联想记忆:

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
From the themed collection: 这些公积金新规不可不知
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
From the themed collection: 瓷砖石材新品夺眼球
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

这部13个小时的,关于长毛狗经历的影片花了45年才来到美国的影院,但时机却恰到好处。里维特先生淘气地在巴黎、法国文学与若干永恒的哲学谜题(真实的本质是什么,我们怎么知道我们知道,因与果之间的联系)之间徜徉,它既是一个迷人的,被重新发觉饿出来的艺术品,片长简直疯狂;与此同时,也警示着电影的未来。一切都已经做过了,一切都仍然是可能的。
BrandZ表示,最具价值品牌的表现超过金融市场,这说明了它们的财务实力和对股东的价值。
单词portion 联想记忆:

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
From the themed collection: 房租异常上涨意味着房价拐点临近
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

The artefact which has a flat base was found inside an ancient tomb in the Xuyi County in western Jiangsu in 2009. It has been kept at the Nanjing Museum the capital of Jiangsu Province.
“我们现在从中国看到的情况不仅仅是巴西一国的现象,我们在整个拉美都看到了同样的情况,中国对所有市场的出口都在下降,”负责马士基航运在巴西、巴拉圭、乌拉圭和阿根廷业务的执行董事安东尼奥?多明格斯(Antonio Dominguez)表示,“已经连续几个季度出现这种情况,但随着我们进入(2016)年,这种局面变得越来越明显了。”

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

此外,该报告还指出,雨果博斯、雪佛兰和舒洁则跌出了该榜单。
['?nim'pl?im?nt]
Scarlett Johansson of Captain America: Civil War was third at $25 million, down nearly 30 percent from 2015.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

Company: (Wonderbag) Natural Balance

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

他们先在伦敦中心广场上开了个熊猫聚会,接着来到特拉法加广场打太极。这一切都是第一届"感受熊猫"周的特别活动。
Gideon Rachman

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

《风流医生俏护士》首播时,鹰眼和诱捕者这两个角色原本同等重要,也正是在这样的条件下,韦恩·罗杰斯才同意扮演诱捕者约翰。然而,当艾伦·艾尔达开始对这个角色进行改动并对整个剧情走向产生更大影响时,鹰眼使诱捕者这一角色黯然失色。
10.Michigan's Upper Peninsula, the US

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

于上周二发布的《2016胡润IT富豪榜》显示,排在前50名的中国IT富豪的平均财富同比上涨13%,至创纪录的269亿元。
Who was buried here?

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

Trade flows brought China’s balance of trade to $40.82bn, roughly $7.2bn below expectations and down about $3.6bn from November’s revised level of $44.23bn (previously $44.61bn). That balance came to Rmb275.4bn in local-currency terms.
“这可能影响他们一生。”

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

不会。当然,这种情况可能发生,但是只要运气不是太差,梅眼下至少可以确保英国经济不会在2019年因掉落“无协议”悬崖而急剧下滑。2017年12月,“共识预测”(Consensus Forecasts)预测2018年英国将增长1.5%。该机构对日本和意大利的预测值更低,为1.3%。因此英国明年成为G7中经济增长最慢国家的几率应该在四分之一左右。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

今年2月的时候,玛蒂参加了J.Mendel2015秋冬高级成衣发布秀(图)
中国最高纪律监管机构日前表示,去年共有1300名涉嫌经济犯罪的外逃人员回国接受审判,其中腐败官员347人。
然而,还有人认为医生的所作所为可能是受不公平的体制所迫。另一位网友称:“作为一个病人,我更关心他们能否治好我的病,而不是他们发表了多少论文。”
Recipient: Canadian Prime Minister Justin Trudeau

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
From the themed collection: 绿色建材标准推新材料入市
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

The programme focuses on the early careers of the children that are enrolled in the Abby Lee Dance Company in Pittsburgh, Pennsylvania.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

The ranking of 95 schools, up from 90 last year, includes nine institutions, from seven countries, that were ranked for the first time. Frankfurt School of Finance and Management in 41st place is the year’s highest new entrant. The German school has one of the most gender-balanced programmes, with women accounting for 49 per cent of students.
Until now, testing reliably for lead was expensive and meant sending away samples for analysis.
8qFVdkcH4D(jz2U^

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

INDOORS: This house was completed around 1848 and last updated in 2008. The front door has a transom and sidelights of red glass etched with a leaf motif. The first floor has a large living room with crown molding and two fireplaces, one of which warms the formal dining area. Off the living room is a family room with raised wall paneling, a wet bar and another dining area. French doors open to a slate patio. Several rooms have views of Little Narragansett Bay.
“这可能影响他们一生。”

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

谎言3:是的,这挺有道理的。说谎原因:方案二会让我显得毫无头绪。
Stallone's iconic underdog has spent decades inspiring athletes and nonathletes alike to fight for their goals. As a poor local boxer, Rocky gets his break when he enters a fight with World Heavyweight Champion Apollo Creed. Due to his rigorous training and Creed's relative apathy, Rocky becomes the first challenger to ever push Creed through all 15 rounds.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

Of course, the recovery of the job market has been, and probably will remain, incremental. Job growth needs to be much stronger to actually make a big dent in unemployment, which remains high at 7.9%, though down from 10% three years ago.[qh]

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Intel
深化生态文明体制改革。
1961年11月9日,扬妮克?里德在南安普顿大学上空骑着一辆形状非常像飞机的自行车——世界上第一辆会飞的自行车诞生了。这辆自行车被称为南安普顿大学的人力飞机(塞桑普顿大学号)。为使自行车飞离地面,德里克刚开始猛烈地踩脚踏板,然后自行车在离地面1.8米(6英尺)的高处飞行,最终飞行了64米(210英尺)。即使飞行速度很缓慢,飞行距离也很短,但这仍是第一辆会飞的自行车,同时,也是第一辆"人力飞车"。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

这部电影也是为了纪念2005年电视剧发行十周年而拍摄的。
At the last minute he opted instead for Teach First, the educational charity that has become the UK’s biggest recruiter of new graduates. Rather than parachuting into companies that needed restructuring, Mr Ravenscroft started teaching business and economics at Cardinal Pole School, which serves 11-19 year old boys and girls in Hackney, east London.
与此同时,微信恐怕也是腾讯吸引海外用户潜力最大的产品。Forrester的分析师Bryan Wang说,他看到新加坡、印度的同事和朋友也开始出现在了自己的微信好友列表中。
韩云平称,去年质检总局组织了两次大规模的检查,涉及超过5300批的进口消费品,例如空气净化器、汽车刹车块、家用电器和服装等,其中超过1500批的商品不合格。

Graphical abstract: Length-scale dependence of protein hydration-shell density
From the themed collection: 京城千余家具厂商九成面临转移
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

Technically it is a project of the 10-member Association of Southeast Asian Nations to bring all of its trade deals in the region under one umbrella. It also lacks the ambition on many fronts of the TPP.
Local-level work experience will advantageous for applicants, with personnel with more than two years of experience at this level given some advantage.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: 20城出台租赁住房新政
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

n. 无限
全食CEO约翰麦基的《自觉资本主义》(Conscious Capitalism)一书让公司高管们不得不思考这样一个观点,那就是处于最佳运转状态的企业能为所有利益相关方创造价值,而不仅仅是投资者。麦基认为,主要利益相关方包括顾客、员工、供应商、社会以及环境。他以好市多、西南航空(Southwest Airlines ,《财富》500强)和谷歌(Google,《财富》500强)为例,说明思维超越利润能够打造更强大而、更高效的公司。
Carry out deleveraging in an active and prudent way.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
From the themed collection: 2016年第一季度人造板问题频发
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“Even if you have made your peace with a Fed rate rise there are other reasons to be nervous,” said David Hauner, head of emerging markets at Bank of America Merrill Lynch, who points to falling oil prices and the slowdown in China to illustrate why market volatility measured by the CBOE’s Vix index, a barometer of investor sentiment, has been elevated since August.
vt. 妥协处理,危

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