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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

The dollar value of China’s exports and imports grew in November after two months of contraction and in the face of a rally by the greenback that followed last month’s US presidential election.
The contiguous United States set a temperature record in 2012, a year of scorching heat waves and drought. But, mostly because of the unusual chill in the East, 2014 was only the 34th warmest year on record for the lower 48 states.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

1q_LRV!0kJXXtQDOIg7_
公司:女性博客网站BlogHer

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
From the themed collection: 农地改革呼唤更多创意
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 建材企业的日子也不好过
Open Access Perspective

Soft matter science and the COVID-19 pandemic

According to the financial data provider Wind Information Co Ltd, listed companies in China's A-share market earned 2.47 trillion yuan in profits last year. Of those listed companies, 2000 plan to pay out 700 billion yuan to their shareholders.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

52% of the world lived in extreme poverty in 1981. This number dropped down by 21% in 2010, as 721 million fewer people no longer live in absolute poverty.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

n. 游艇,快艇 vi. 驾快艇
Mr Erdogan’s escalation comes in the midst of a vitriolic tit-for-tat between Ankara and The Hague, which began at the weekend after Dutch officials barred Turkish ministers from campaigning in Turkish communities inside the Netherlands.
Hurricane Irma
Loyal employees of this auto services company are rewarded on their 10th anniversary -- and every five years after --with a weekend getaway at a resort in Boca Raton, Fla. (The company is headquartered just 15 minutes away.)

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

源于:sloth(n (对工作)懒惰)slou=slow,ch吃:吃得慢-无精打采的样子
adj. 粗糙的,粗略的,粗暴的,艰难的,讨厌的,不适的
After Zhou contaminated the water, one of Zhou's classmates surnamed Tang noticed that the water coming out of the dispenser was milky and had a pungent scent.
episode

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

The Beijing Tourism Development Commission noted that the country's battle with pollution is another obstacle cities face in attracting inbound tourists.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
From the themed collection: 北京离职后如何提取住房公积金
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

World's Most International Universities Ranking 2016 by The Times Higher Education included 200 universities from 28 countries. It employed indicators such as the proportion of international staff, the number of international students and research papers published with at least one co-author from another country of each institution.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

周二在华盛顿DC倒下的大树把一条街拦住了。
Meanwhile, in an unfortunate red carpet faux pas, Pink and Shakira both showed up in the same Balmain dress.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

China denies any wrongdoing and says it is working to tackle problems of industrial overcapacity that have become more acute as its economy has slowed.
添加方式2.搜索微信号ikekenet添加即可。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

第一次跻身品牌价值100强的是法国时尚品牌迪奥和硅谷的汽车制造商特斯拉汽车公司,他们分别位列第89名和第100名。
adj. 有限的,被限制的

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

“BlackBerry has not engaged in discussions with Samsung with respect to any possible offer to purchase BlackBerry,” the company said in a statement issued Wednesday afternoon. “BlackBerry’s policy is not to comment on rumors or speculation, and accordingly it does not intend to comment further.”
But what drives the underlying optimism or pessimism? Koudijs, working with Hans-Joachim Voth at the UniversitatPompeuFabra in Barcelona, found surprising answers.
1. China’s Economy.China is the second largest consumer of oil in the world and surpassed the United States as the largest importer of liquid fuels in late 2013. More importantly for oil prices is how much China’s consumption will increase in the coming years. According to the EIA, China is expected burn through 3 million more barrels per day in 2020 compared to 2012, accounting for about one-quarter of global demand growth over that timeframe. Although there is much uncertainty, China just wrapped up a disappointing fourth quarter, capping off its slowest annual growth in over a quarter century. It is not at all obvious that China will be able to halt its sliding growth rate, but the trajectory of China’s economy will significantly impact oil prices in 2015.
他们必须发自内心地明白,通过操纵选举、打击异见或者骚扰反对派让临时权力永久化是不合法的。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

单词toxic 联想记忆:

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

They are calculated using a methodology that focuses on a school's research performance and reputation, not its specific undergraduate or graduate programs. This is a separate methodology than those used for other US News rankings such as Best Colleges and Best Graduate Schools.
德国

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

《一个开车从来不回头看的沙特女子》(A Saudi Woman Who Got Behind the Wheel and Never Looked Back)

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

马自达获得了最佳轿车品牌的称号。汽车媒体一直很青睐马自达的表现,而如今的马自达汽车都在精致的内部设置和强大的驱动力上赢得了积极的反馈。上图的2016马自达第三代,在美国新闻小巧车排名中摘得桂冠,它的精准操控,强大加速度和高端室内布局,赢得了大多数汽车评论家称赞。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

1999:H9N2传染人类1999: H9N2 Infects Humans
9. "Vikings" (2.3 million)
欧盟的美洲布局
n. 隧道,地道

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

Exports declined 6.9 per cent in October from a year earlier, deteriorating from the 3.7 per cent fall the previous month as weak global demand and higher Chinese costs led to slumping shipments of the cheap Chinese goods that have flowed to the world in the last decade.
“The Fed was much more aggressive than expected,” Mr Koepke says. “Taking markets by surprise was clearly not the way to go.” (This was before the Fed began making regular public statements after its monetary policy meetings.)
卷铺走人的时候
‘Jordan,’ ‘harley,’ ‘robert,’ ‘matthew,’ ‘daniel,’ ‘andrew,’ ‘andrea,’ and ‘joshua’ all made it on the list – along with ‘football,’ and ‘lakers.’
《那年花开月正圆》并非改编自小说,而是基于真实人物女商人周莹的故事拍摄的。周莹生在清朝(1644-1911),是当时的陕西省女首富。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
From the themed collection: 社保拟减持近百亿元交行股票
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

“Today you have to shop by image,” Mr. Nathan said. “But if you are brave and don’t follow fashion, there are opportunities.”
在本周达沃斯年会上,政策制定者、政治人士以及商业领袖达成了这种谨慎乐观的共识,这种局面是自2007年以来历届世界经济论坛所不曾看到的。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

[st?:]

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

豆瓣网友“Jiuyuehuashang”称:“剧中,爱情就是女主唯一的追求。她生命的意义似乎就是找一个真命天子谈情说爱。不对,不是一个,是三四个。”

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

接受一份谋生型的工作有两个弊端。这样做会让你在求职中分心,而且潜在雇主对你以前的专业形象会有所怀疑。
[k?'p?siti]
10月1日
Allianz

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

Wang Rongzhen在采访中表示,“我们就是要卖车,如果厂家不提供车型,我们就卖不下去了,也只能退网。”他估计经销商每年亏损300-1000万元。目前,现代汽车在中国有近40家进口经销商,其中30家经销商要求退网赔偿。
LONDON — In the 1970s, the British comedian Tommy Cooper used to tell a joke about asking an auction house to value a violin and a painting that he had discovered in an attic. The good news, he was told, is that they were made by Stradivarius and Rembrandt. The bad news was that the painting was by Stradivarius and the violin was by Rembrandt.
appear出现+ance表名词,“性质,状况”→出现;外表
Harvard Business School, London Business School (LBS) and MIT Sloan School of Management, three of the MBA ranking’s longstanding heavyweights, all lost ground to their competitors. Harvard drops two places to fourth, the first time in nine years that the Boston school has been outside the top three. London Business School falls three places to sixth, its lowest position in 14 years. MIT Sloan School of Management falls to 13th place, the first time in 10 years that it has been outside the top 10.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

中国早已超越了俄罗斯成为紧随美国之后的世界第二大强国。
The film screens in China reached 41,179 as of the end of 2016 with another 1,612 cinemas and 9,552 film screens built during the year, according to a report by People's Daily.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Over the next few years, large residential buildings will have to comply with Local Law 87, which requires them to audit energy usage and keep systems running at peak efficiency. Residential buildings are the city’s largest source of greenhouse gas emissions, accounting for 37 percent of the total. “The one hot-button topic is energy. How do buildings become more energy efficient?” said Dan Wurtzel, the president of FirstService Residential New York, which manages more than 500 properties. “If a third of your operating budget is related to energy and you can now reduce that cost, you can take pressure off the need for a maintenance increase.”
获奖者:加拿大总理贾斯廷·特鲁多
1. What big brother is eating isn’t noodles, but loneliness.
今年,科学家们研究了对冲突表现出愤怒、拖延的消极策略,他们发现,久而久之这些反应会以某些特定方式预示与健康相关的变化。
“有些人说自己去吃午饭了,然后一去不回。”

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

1.戛纳也有软肋
库克决定通过增加派息和回购股票扩大其现金返还计划,帮助缓和了与维权投资者的关系。目前它总共向股东返还现金940亿美元。最终,库克以足够的坚忍抵挡住挑战,迎来了iPhone又一波增长捷报,以及从乔纳森?艾夫爵士(Sir Jonathan Ive)的设计室诞生的新产品。
注册人数:388人

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
From the themed collection: 未来已来,新工具赋能城市新时代
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

20. 对电影爱好者的最佳建议。8月学者韦勒·温斯顿·迪克森(Wheeler Winston Dixon)发出了警告:“如果你上亚马逊,看到什么精彩的黑白电影卖三美元,或者其他什么外国电影和鲜为人知的电影,赶快买下来,因为它就要绝版了,他们不会再出版它们了。”成千上万这种VHS格式的电影不会被做成DVD格式或蓝光格式,迪克森警告说。而下载的美丽新世界(又名电子销售)明年将是好年头。
达奇斯说:阿迪达斯在今年的12个月里增加了3400万名新粉丝。公司把粉丝们带动了起来,粉丝们一整年都在进行积极的讨论,公司因而从中受益。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
From the themed collection: “限购升级”:去年头号热点新闻
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

By turns breathtaking, hilarious and disturbing, Jonathan Glazer’s extraordinary, erotic film achieves a rare blend of fantasy and realism
The cost of living the Australian dream has surged with Sydney and Melbourne among the five most expensive cities in the world, outstripping most European and US locations, according to an annual survey released on Monday.
This year's new college grads entering the workforce are being offered an average monthly salary of 4,014 yuan ($582), and about one-third of them chose to work in first-tier cities, according to survey results released by zhaopin.com, a Chinese online recruitment service provider.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

综合考虑,这些事实与战略规划凸显了中国航天工业的认知——为了成为有竞争力的全球飞机制造商,中国需要拓宽行业的广度与深度。在他们掌握了价值链的两端——飞机设计与集成组装后,中国意识到长期处于价值链中游的组装和子系统地位将摧毁他们的航空业。这就是为什么中国雄心勃勃地与波音、空客等飞机制造商以及美国通用电气公司、劳斯莱斯等发动制造商竞争,形式前所未有地激烈。
从什么时候起,冬季成了一年中电视节目最丰富的季节?今年秋天有许多首播电视剧做了有组织的盛大宣传,获得不少关注,但更多有趣的剧集还是在一年中的前三个月中登陆有线台、无线台和网络。
时间:2009-11-11 编辑:vicki

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

《法律与秩序:特殊受害者》(Law & Order: SVU):NBC频道的这部电视剧上一季中的危机仿佛是从肥皂剧中搬来,发生了各种大事,奥利维亚(Olivia,玛莉丝卡·哈吉塔[(Mariska Hargitay]饰)经历了许多危险——喜欢跟踪的变态强奸犯,折磨人的婚外恋,新生婴儿,现在这一切终于平息下来。在今年的第16季中,侦探们回到了重要的性犯罪上,其中一集的灵感来自雷·赖斯(Ray Rice),讲述的是从监控录像中看到一个著名体育广播员殴打自己的妻子。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

美联储去年花了六个多月的时间暗示其有意退出第三轮购债计划,这种可能性时常扰动着市场。目前美联储仅处于退出购债计划的第一阶段。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

9.The Bling Ring
这位腾讯公司员工说道:“我们希望她的妈妈能出面协助我们一起调查此事。如果用户确实13岁,未经允许花钱,那么我们可以协调退还。”

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

The report didn't comment on potential factors influencing the numbers, but many – including members of the opposing political party – are laying the blame squarely at the feet of government cost-cutting.
艾米莉·拉塔基科斯基想(在红毯秀上)抢镜头,她选择了一件经典的舞会礼服,礼服上编织着非常别致的花纹。这位出演了《我们是你的朋友》这部影片的女演员选择了一件黑色半透明且有着精致的透空图案的礼服来展示自己举世闻名的身材。
It is the first time that EMBA-Global, the joint programme delivered by London Business School and Columbia Business School, has dropped out of the top five.
When researchers at the University of Illinois set out to create a device that identifies chemicals by their scent, they didn't settle for the sensitivity of the human nose. Instead, they created an artificial nose that uses the smell of bacteria to identify and diagnose specific diseases.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
From the themed collection: 大盘反弹 抄底LED照明产业正当时
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

立场:承诺聘用老兵
n. 日历,月历,日程表

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

[?'pru:v?l]
肠道细菌正以我们想像不到的方式干扰着我们。新的研究指出,像帕金森综合症等神经退行性疾病实际上可能始于肠道,而不是大脑。越来越多的证据显示,慢性疲劳综合征可能要归咎于人体内的微生物群系。随着肠道细菌显示出控制食欲以及改变大脑结构的迹象,而且有引起大脑损伤而导致中风的表现,我们的这个小过客(肠道细菌)有着不容忽视的力量。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

1. "Game of Thrones" (5.9 million)

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

赛瑞戴维森
The Jungle Book will be released worldwide on April 15, 2016.
第六步 找到你的“花生”
Contrary to the consensus view -- which assumes that smartphones in China will only get cheaper -- she cites research showing that the average selling price stablized last yearand has actually started to increase as Chinese users trade up to higher-quality smartphones.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
From the themed collection: 欧普照明净利下降 OEM模式现隐忧
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

This groundbreaking fight is loosely based on a bout between Chuck Wepner and Muhammad Ali, in which the "everyman" Wepner managed to become one of the four men to knock Ali down in his career. Just like in the film, Wepner pushed Ali through 15 rounds despite looking (and feeling) like he'd been hit by a truck. While both he and Rocky ended up losing their fights on a technicality, Wepner wins in our book for inspiring such an awesome character.
Emily Ratajkowski managed to steal the show, opting for a seriously saucy twist on the classic ballgown. Opting for a semi-sheer lacey black number, the We Are Your Friends actress ensured her world-famous figure was on display.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

五大发展理念:创新、协调、绿色、开放、共享的发展理念
亚洲的商界女性在崛起:整个亚洲地区在榜单上的表现都非常抢眼,从中国和新加坡到新西兰和泰国,都能找到女强人的身影。亚洲的女性企业家群体正在崛起,例如张欣(排名第50)、孙亚芳(排名第77)和周凯旋(排名第80)。在政界,亚洲女性也在施展自己的抱负,例如新上榜的韩国总统朴槿惠(排名第11),缅甸反对派领袖、国会议员昂山素季(排名第29),澳大利亚总理茱莉亚·杰拉德(排名第28),以及泰国总理英拉·西那瓦(排名第31)。
4、慧眼识香。邦德眼光敏锐,能辨认出孰敌孰友。这种品质常见于性开放者。007很容易识出对他有意的女人,有科学证明,帅哥往往擅长于此。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

报道称,这些公共脸书群组的名字包括,“哈佛前1%精英少年表情包群”、“UCLA超变态青少年表情包群”、“USC被宠坏的小少年表情包群”等。
在即将结束的2014年,标普500指数再次实现亮眼增长,而那些本欲跑赢该指数的基金经理们,表现则没那么出色。Lipper公司称,截止11月底,85%的活跃股票型共同基金经理业绩低于标普500指数。而在正常的年份里,跑赢该指数的基金经理比例是今年的两倍,也就是说,通常只有约三分之二的基金表现不如标普500指数。Lipper公司称,这是30年来活跃基金经理相对大盘表现最差的一年。
中央纪委国际合作局局长腊翊凡表示:“在中共中央的领导下,我们将扩大与有关国家的司法合作,使腐败的外逃人员不存在“避罪天堂”。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

周日也就是张天羽的作品被谷歌展示的前一天,她接受纽约长岛报纸《新闻日》的采访,表示自己对获奖感到兴奋,但不会熬夜等自己的作品上线。
在去年11月29日,共计约有93万人参加国家公务员考试,同比下降了60000人。不过,提供的2.7万个招聘岗位则创下了新高。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
From the themed collection: 中国智能家居或因无专利集体阵亡
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

2016年即将上映的电影都是鸿篇巨制,众多佳片能让你一饱眼福。这些影片包括:《蝙蝠侠大战超人:正义黎明》、《美国船长3:内战》、《神奇动物在哪里》、《海底总动员2》、《星球大战:侠盗一号》、《X战警:天启》、《独立日2:复活》、《魔兽世界》以及《自杀小队》等。
n. 版权,著作权
1. Apple. Brand love: 57% / Rank: 32

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

有些人则特地请人代劳:
《好时光》

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

vt. 包含,容纳,克制,抑制
So I don't know what will happen in 2014--and neither does anyone else. What I imagine, though, looks like this:
格陵兰鲨活得很久

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

Aoki-san is a pleasure to work withon storyboard. With Aoki-san on the team it feels like a sure thing. The visionof these animations will be perfect.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

《东方快车谋杀案》
[p?'tenl]

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
From the themed collection: 温榆河孙河段将现湿地水乡景观
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

9) I would rather keep people at a distance 0 1 2 3 4
Callabro,喜欢唱歌剧的男孩组合在经过不懈努力之后成功成为了本年度的英国达人秀冠军,最具天赋的歌唱组合。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

Beijing is pushing hard to conclude the Regional Comprehensive Economic Partnership by the end of the year. The deal has long been called China’s answer to the Trans-Pacific Partnership and its bid for regional trade hegemony.
单词expansion 联想记忆:

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

The latest government figures were a big jump from data in mid-December, when1,200 people were said to have left or are seeking to leave to battle alongside jihadists.
我们的外汇储备是充裕的,是足以支付进口和满足短期偿债需要的。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
From the themed collection: 租户人身安全亟须立法明确保障
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

I know many of you met your former spouse at the company. But the thing is, for every one of you, there are five people it doesn't work out as well for. And your office romance can and will be held against you.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

不过另一个因素也影响着最新一集《007》的计划,主演“詹姆斯-邦德”丹尼尔-克雷格全心投入于演出《千禧年三部曲》,而其中的《龙文身的女孩》正在紧张拍摄中。而目前电影公司也没有遴选新一任007的打算,若果丹尼尔三度出演这一角色,电影至少得等到2014年才能上映。
The Atlanta-based group expects sales, adjusted for acquisitions, divestitures and currency fluctuations, to rise 3 per cent, compared with its earlier forecast of between 4 per cent and 5 per cent.
单词intended 联想记忆:
《出生于缅甸皇室的她成为军阀和大毒枭》(The Female Warlord Who Had C.I.A. Connections and Opium Routes)

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

陆金所是最大的一家。它是中国平安保险(Ping An Insurance)的子公司,平安也是陆金所最大的股东。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

If there are nine or 10 best picture nominees, it could grab a spot. Jordan Peele's screenplay looks certain to be recognized.
For: The Los Angeles Critics Association gave it their top prize.
在今年的榜单上,美国学校恢复了自己的优势,上榜的美国学校数量增至51所。2016年,这一数据首次跌破50,降至47所。在8所新上榜或重新上榜的学校中,有6所来自美国。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

日历一页一页地翻到了12月,一些球队是时候考虑垫底的不可避免性了。那么,哪些球队应该开始着手垫底,哪些球队还需要观望,而哪些球队应该放弃这种打算呢。Flanns 和Zillz将会就这一问题展开讨论。
adj. 最高的,至上的,极度的

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

总部位于芝加哥的竞争对手科尔尼(AT Kearney)也在为领导层变动做准备,计划于2018年第一季度投票决定接替约翰奥利格(Johan Aurik)的人选。管理合伙人最多担任两个任期,而奥利格已经期满。预计他的继任者将专注于让科尔尼做大,摆脱中等规模参与者之列。
娱乐时尚:性感林赛罗韩大"血拼"

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

mortality

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

1. Bubble With No Name Yet triggers the biggest crash in 30 years
Consider:
欧洲管理学院协会(Cems)管理硕士项目——由30家商学院联合提供的国际项目——排名第九,比2015年下滑五名。该项目上一次上榜是在2015年。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

Qube会提醒你注意垃圾回收,在垃圾最后被倒出来的时候进行监控,并告诉你更换空气清新剂。但这些人们通常可以通过嗅觉和其他感觉器官来判断。现在有一个300美元的“优雅”不锈钢,会不断用讨人厌的移动警报提醒你。
'It's going to get volatile to the upside,' he said.
Jude Webber
教育部在一场新闻发布会上表示,全球大多数的留学生都是来自中国。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

[.ent?'teinm?nt]
6. 《出租车》(Taxi),导演贾法·帕纳西(Jafar Panahi)。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: “以房养老”保险缘何遇冷?
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

The decaying feet, some dating back to 1967, were being 'cleaned up', plumped up and whitened at the 'foul-smelling' plant using bleach and other chemicals, before being prepared for sale.
“我们现在从中国看到的情况不仅仅是巴西一国的现象,我们在整个拉美都看到了同样的情况,中国对所有市场的出口都在下降,”负责马士基航运在巴西、巴拉圭、乌拉圭和阿根廷业务的执行董事安东尼奥?多明格斯(Antonio Dominguez)表示,“已经连续几个季度出现这种情况,但随着我们进入(2016)年,这种局面变得越来越明显了。”
据一家行业报道,中国的网红预计能在2016年创造出高达580亿元(87亿美元)的市场,远超去年的440亿元的票房。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

About this collection

樟宜机场集团总裁李绍贤先生表示:“连续五年获得Skytrax世界最佳机场的殊荣,这是对整个樟宜机场五万多名职员巨大的鼓励,我们每一位员工都极富热情,并且希望留给每一位旅客最难忘的候机经历。”
同时,根据这一最新调查显示,2015年我国男女比例的差距也有所缩小。从性别构成看,男女人口性别比例已由2010年的105.2降至去年的105.02。

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